Multiple Hepatitis B Virus (HBV) Quasispecies and Immune-Escape Mutations Are Present in HBV Surface Antigen and Reverse Transcriptase of Patients With Acute Hepatitis B.

doi:10.1093/infdis/jiw049

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Article

Multiple Hepatitis B Virus (HBV) Quasispecies and Immune-Escape Mutations Are Present in HBV Surface Antigen and Reverse Transcriptase of Patients With Acute Hepatitis B.

The Journal of infectious diseases - 15 Jun 2016

Aragri Marianna, Alteri Claudia, Battisti Arianna, Di Carlo Domenico, Minichini Carmine, Sagnelli Caterina, Bellocchi Maria Concetta, Pisaturo Maria Antonietta, Starace Mario, Armenia Daniele, Carioti Luca, Pollicita Michela, Salpini Romina, Sagnelli Evangelista, Perno Carlo Federico, Coppola Nicola, Svicher Valentina

Abstract excerpt

BACKGROUND: This study characterizes and defines the clinical value of hepatitis B virus (HBV) quasispecies with reverse transcriptase and HBV surface antigen (HBsAg) heterogeneity in patients with acute HBV infection. METHODS: Sixty-two patients with acute HBV infection (44 with genotype D infection and 18 with genotype A infection) were enrolled from 2000 to 2010. Plasma samples obtained at the time of the...

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PMID: 26908731
DOI: 10.1093/infdis/jiw049

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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