Article
Downstream sequence-dependent RNA cleavage and pausing by RNA polymerase I.
The Journal of biological chemistry - 31 Jan 2020
Scull Catherine E, Clarke Andrew M, Lucius Aaron L, Schneider David Alan
Abstract excerpt
The sequence of the DNA template has long been thought to influence the rate of transcription by DNA-dependent RNA polymerases, but the influence of DNA sequence on transcription elongation properties of eukaryotic RNA polymerase I (Pol I) from Saccharomyces cerevisiae has not been defined. In this study, we observe changes in dinucleotide production, transcription elongation complex stability, and Pol I pausing...
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