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Article

RNA polymerase II mutations conferring defects in poly(A) site cleavage and termination in Saccharomyces cerevisiae.

G3 (Bethesda, Md.) - 1 Feb 2013

Kubicek Charles E, Chisholm Robert D, Takayama Sachiko, Hawley Diane K

Abstract excerpt

Transcription termination by RNA polymerase (Pol) II is an essential but poorly understood process. In eukaryotic nuclei, the 3' ends of mRNAs are generated by cleavage and polyadenylation, and the same sequence elements that specify that process are required for downstream release of the polymerase from the DNA. Although Pol II is known to bind proteins required for both events, few studies have focused on Pol...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 23390594
DOI: 10.1534/g3.112.004531
PMCID: PMC3564978

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Source receipt: pubmed, retrieved 7 Sept 2026.

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