Article
A template-proximal RNA paired element contributes to Saccharomyces cerevisiae telomerase activity.
RNA (New York, N.Y.) - 1 Nov 2003
Seto Anita G, Umansky Kfir, Tzfati Yehuda, Zaug Arthur J, Blackburn Elizabeth H, Cech Thomas R
Abstract excerpt
The ribonucleoprotein complex telomerase is critical for replenishing chromosome-end sequence during eukaryotic DNA replication. The template for the addition of telomeric repeats is provided by the RNA component of telomerase. However, in budding yeast, little is known about the structure and function of most of the remainder of the telomerase RNA. Here, we report the identification of a paired element located...
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