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Article

Anterior Cingulate Structure and Perfusion is Associated with Cerebrospinal Fluid Tau among Cognitively Normal Older Adult APOEɛ4 Carriers.

Journal of Alzheimer's disease : JAD - 1 Jan 2020

Hays Chelsea C, Zlatar Zvinka Z, Meloy M J, Osuna Jessica, Liu Thomas T, Galasko Douglas R, Wierenga Christina E

Abstract excerpt

Evidence suggests the ɛ4 allele of the apolipoprotein E (APOE) gene may accelerate an age-related process of cortical thickening and cerebral blood flow (CBF) reduction in the anterior cingulate cortex (ACC). Although the neural basis of this association remains unclear, evidence suggests it might reflect early neurodegenerative processes. However, to date, associations between cerebrospinal fluid (CSF)...

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Source

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Identifiers

PMID: 31743999
DOI: 10.3233/JAD-190504
PMCID: PMC7310575

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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