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Article

APOE-by-sex interactions on brain structure and metabolism in healthy elderly controls.

Oncotarget - 29 Sept 2015

Sampedro Frederic, Vilaplana Eduard, de Leon Mony J, Alcolea Daniel, Pegueroles Jordi, Montal Victor, Carmona-Iragui María, Sala Isabel, Sánchez-Saudinos María-Belén, Antón-Aguirre Sofía, Morenas-Rodríguez Estrella, Camacho Valle, Falcón Carles, Pavía Javier, Ros Domènec, Clarimón Jordi, Blesa Rafael, Lleó Alberto, Fortea Juan

Abstract excerpt

BACKGROUND: The APOE effect on Alzheimer Disease (AD) risk is stronger in women than in men but its mechanisms have not been established. We assessed the APOE-by-sex interaction on core CSF biomarkers, brain metabolism and structure in healthy elderly control individuals (HC). METHODS: Cross-sectional study. HC from the Alzheimer's Disease Neuroimaging Initiative with available CSF (n = 274) and/or 3T-MRI (n =...

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Source

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Identifiers

PMID: 26397226
DOI: 10.18632/oncotarget.5185
PMCID: PMC4694943

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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