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Article

Interaction of APOE, cerebral blood flow, and cortical thickness in the entorhinal cortex predicts memory decline.

Brain imaging and behavior - 1 Apr 2020

Hays Chelsea C, Zlatar Zvinka Z, Meloy M J, Bondi Mark W, Gilbert Paul E, Liu Thomas, Helm Jonathan L, Wierenga Christina E

Abstract excerpt

The ε4 allele of the apolipoprotein E (APOE) gene, a risk factor for cognitive decline, is associated with alterations in medial temporal lobe (MTL) structure and function, yet little research has been dedicated to understanding how these alterations might interact to negatively impact cognition. To bridge this gap, the present study employed linear regression models to determine the extent to which APOE genotype...

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Share to Apolipoprotein E4
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32048144
DOI: 10.1007/s11682-019-00245-x
PMCID: PMC7165062

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