Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interaction of age and APOE genotype on cerebral blood flow at rest.

Journal of Alzheimer's disease : JAD - 1 Jan 2013

Wierenga Christina E, Clark Lindsay R, Dev Sheena I, Shin David D, Jurick Sarah M, Rissman Robert A, Liu Thomas T, Bondi Mark W

Abstract excerpt

We investigated the impact of APOE genotype on cerebral blood flow (CBF) in older and younger adults. Forty cognitively normal older adults (16 ε4 carriers, 24 non-ε4 carriers) and 30 younger adults (15 ε4 carriers, 15 non-ε4 carriers) completed a resting-state whole-brain pulsed arterial spin labeling magnetic resonance scan. Main effects of aging were demonstrated wherein older adults had decreased gray matter...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Mapping
Share to Cerebrovascular Circulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Functional Laterality

Share to Image Processing, Computer-Assisted

Share to Mental Status Schedule

Share to Neuropsychological Tests

Share to Spin Labels

Source

Open in PubMed Open full text

Identifiers

PMID: 23302659
DOI: 10.3233/JAD-121897
PMCID: PMC4124882

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interaction of age and APOE genotype on cerebral blood flow at rest.PMID 23302659Read ↗

Differential effects of the APOE genotype on brain function across the lifespan.Semantic proximity Read ↗

Effect of mild cognitive impairment and APOE genotype on resting cerebral blood flow and its association with cognition.Semantic proximity Read ↗

APOE related alterations in cerebral activation even at college age.Semantic proximity Read ↗

Interactive effect of apolipoprotein e genotype and age on hippocampal activation during memory processing in healthy adults.Semantic proximity Read ↗

Impact of sex and APOE ε4 on age-related cerebral perfusion trajectories in cognitively asymptomatic middle-aged and older adults: A longitudinal study.Semantic proximity Read ↗

APOE epsilon4 genotype and longitudinal changes in cerebral blood flow in normal aging.Semantic proximity Read ↗

Associations between age, sex, APOE genotype, and regional vascular physiology in typically aging adults.Semantic proximity Read ↗

Neuroimaging and <i>APOE</i> Genotype: A Systematic Qualitative ReviewSemantic proximity Read ↗

Interaction of APOE, cerebral blood flow, and cortical thickness in the entorhinal cortex predicts memory decline.Semantic proximity Read ↗

The effects of APOE-ε4 on the BOLD response.Semantic proximity Read ↗

Anterior Cingulate Structure and Perfusion is Associated with Cerebrospinal Fluid Tau among Cognitively Normal Older Adult APOEɛ4 Carriers.Semantic proximity Read ↗

Reduced cerebrovascular reactivity in young adults carrying the APOE ε4 allele.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.