Article
[Using next generation sequencing technology to analyze gene mutations in patients with acute myeloid leukemia and the impact on prognosis].
Zhonghua yi xue za zhi - 29 Oct 2019
Zhao C X, Wang J M, Li J M, Zou S H, Chen F Y, Liang A B, Hou J, Hu X X, Zhang Y X, Gu S Y, Zhu J Y, Li P, Du J, Yang Y N, Qin Y W, Wang X R, Wang C
Abstract excerpt
Objective: To analyze the distribution of gene mutations in newly diagnosed acute myeloid leukemia (AML) patients, based on next generation sequencing technology (NGS) and to evaluate their value in AML risk stratification. Methods: The study analyzed 453 newly diagnosed AML(excluded acute promyelocytic leukemia, APL) patients from seven hospitals in Shanghai, from January 1st 2014 to December 31th 2017. RNA and...
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