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Article

Gene mutation patterns of Chinese acute myeloid leukemia patients by targeted next-generation sequencing and bioinformatic analysis.

Clinica chimica acta; international journal of clinical chemistry - 1 Apr 2018

Han Xiaoyu, Li Wei, He Na, Feng Panpan, Pang Yihua, Ji Chunyan, Ma Daoxin

Abstract excerpt

PURPOSES: The conventional risk stratification of acute myeloid leukemia (AML), based on cytogenetics, cannot meet the demand for accurate prognostic evaluations. In recent years, gene mutations are found to be potential markers for more accurate risk stratification, but reports on mutation screening of Chinese AML are limited. We aim to display the mutation patterns of Chinese AML patients, reveal the...

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Identifiers

PMID: 29309772
DOI: 10.1016/j.cca.2018.01.006

Genes

FLT3
SRSF2
TET2
IDH1

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