Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Characteristics and prognostic significance of genetic mutations in acute myeloid leukemia based on a targeted next-generation sequencing technique.

Cancer medicine - 1 Nov 2020

Wang Rui-Qi, Chen Chong-Jian, Jing Yu, Qin Jia-Yue, Li Yan, Chen Guo-Feng, Zhou Wei, Li Yong-Hui, Wang Juan, Li Da-Wei, Zhao Hong-Mei, Wang Bian-Hong, Wang Li-Li, Wang Hong, Wang Meng-Zhen, Gao Xiao-Ning, Yu Li

Abstract excerpt

To explore the characteristics and prognostic significance of genetic mutations in acute myeloid leukemia (AML), we screened the gene mutation profile of 171 previously untreated AML patients using a next-generation sequencing technique targeting 127 genes with potential prognostic significance. A total of 390 genetic alterations were identified in 149 patients with a frequency of 87.1%. Younger age and high...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Beijing
Share to High-Throughput Nucleotide Sequencing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leukemia, Myeloid, Acute

Share to Nucleophosmin

Share to Predictive Value of Tests

Share to Recurrence

Share to Remission Induction

Share to Risk Assessment

Source

Open in PubMed Open full text

Identifiers

PMID: 32970934
DOI: 10.1002/cam4.3467
PMCID: PMC7666719

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Characteristics and prognostic significance of genetic mutations in acute myeloid leukemia based on a targeted next-generation sequencing technique.PMID 32970934Read ↗

Gene mutation patterns of Chinese acute myeloid leukemia patients by targeted next-generation sequencing and bioinformatic analysis.Semantic proximity Read ↗

[Using next generation sequencing technology to analyze gene mutations in patients with acute myeloid leukemia and the impact on prognosis].Semantic proximity Read ↗

Mutation profile of acute myeloid leukaemia in a Chinese cohort by targeted next-generation sequencing.Semantic proximity Read ↗

Genomic Mutation Profiles of Patients with Acute Myeloid Leukemia in Korea: a Single-Center Experience.Semantic proximity Read ↗

Difference in gene mutation profile in patients with refractory/relapsed versus newly diagnosed acute myeloid leukemia based on targeted next-generation sequencing.Semantic proximity Read ↗

Gene mutation analysis using next-generation sequencing and its clinical significance in patients with myeloid neoplasm: A multi-center study from China.Semantic proximity Read ↗

Genomic mutation patterns and prognostic value in de novo and secondary acute myeloid leukemia: A multicenter study from China.Semantic proximity Read ↗

Mutation profile and associated clinical features in Chinese patients with cytogenetically normal acute myeloid leukemia.Semantic proximity Read ↗

Gene mutation profile and risk stratification in AML1‑ETO‑positive acute myeloid leukemia based on next‑generation sequencing.Semantic proximity Read ↗

Next-generation sequencing-based genetic landscape and its clinical implications for Chinese acute myeloid leukemia patientsSemantic proximity Read ↗

Next-generation sequencing reveals gene mutations landscape and clonal evolution in patients with acute myeloid leukemia.Semantic proximity Read ↗

A targeted next-generation sequencing in the molecular risk stratification of adult acute myeloid leukemia: implications for clinical practice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.