Article
Gene mutation analysis using next-generation sequencing and its clinical significance in patients with myeloid neoplasm: A multi-center study from China.
Cancer medicine - 1 Apr 2023
Li Junnan, Pei Li, Liang Simin, Xu Shuangnian, Wang Yi, Wang Xiao, Liao Yi, Zhan Qian, Cheng Wei, Yang Zesong, Tang Xiaoqiong, Zhang Hongbin, Xiao Qing, Chen Jianbin, Liu Lin, Wang Li
Abstract excerpt
BACKGROUND: Myeloid neoplasms (MN) tend to relapse and deteriorate. Exploring the genomic mutation landscape of MN using next-generation sequencing (NGS) is a great measure to clarify the mechanism of oncogenesis and progression of MN. METHODS: This multicenter retrospective study investigated 303 patients with MN using NGS from 2019 to 2021. The characteristics of the mutation landscape in the MN subgroups and...
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