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Article

Gene mutation profile and risk stratification in AML1‑ETO‑positive acute myeloid leukemia based on next‑generation sequencing.

Oncology reports - 1 Dec 2019

Yu Guopan, Yin Changxin, Wu Fuqun, Jiang Ling, Zheng Zhongxin, Xu Dan, Zhou Jiaheng, Jiang Xuejie, Liu Qifa, Meng Fanyi

Abstract excerpt

Gene mutations play an important role in the development and progression of AML1‑ETO‑positive acute myeloid leukemia (AE‑AML). Nevertheless, the gene mutation profile in this subtype of leukemia remains unclear. In addition, the clinical and prognostic effects of different mutant genes may be underestimated. In the present study, gene sequencing was conducted at diagnosis and relapse with next‑generation...

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Identifiers

PMID: 31638252
DOI: 10.3892/or.2019.7375
PMCID: PMC6826310

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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