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Article

[Comparision of Mutational Spectrum between Elderly and Young Adults with Acute Myeloid Leukemia Based on Next Generation Sequencing].

Zhongguo shi yan xue ye xue za zhi - 1 Feb 2020

Wang Wei-Min, Li Ya-Fei, Sun Ling, Jiang Zhong-Xing, Wan Ding-Ming, Ma Jie, Gan Si-Lin, Wang Fang, Cao Wei-Jie, Sun Hui

Abstract excerpt

OBJECTIVE: To compare the gene mutational spectrum between elderly and young adults with acute myeloid leukemia(AML) based on next generation sequencing(NGS). METHODS: The specimens of 250 AML patients in first affiliated hospital of Zhengzhou University from January 2018 to November 2018 were collected and analyzed retrospectively. The mutation of 22 related genes were detected by using AML NGS chips. Then, the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32027246
DOI: 10.19746/j.cnki.issn.1009-2137.2020.01.003

Genes

IDH2
TET2
DNMT3A
IDH1
SF3B1
U2AF1
KIT
NPM1
SRSF2
ASXL1
FLT3
KRAS
NRAS
RUNX1
TP53
ZRSR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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