Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[Mutational Spectrum and Prognosis Analysis of AML Patients Based on High-Throughput Sequencing].

Zhongguo shi yan xue ye xue za zhi - 1 Apr 2021

Li Jian-Xiong, Liu Heng, Sheng Hong-Xia, Zhang Bin

Abstract excerpt

OBJECTIVE: To investigate the mutational spectrum and its prognostic significance in patients with acute myeloid leukemia (AML). METHODS: The clinical data of 93 patients with newly diagnosed AML who underwent gene mutation detection by high-throughput sequencing (HTS) from March 2014 to April 2018 in our hospital was analyzed retrospectively. The distribution of mutant genes was summarized and the prognostic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ASXL1 gene
Share to CD34 gene
Share to DNMT3A gene

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Leukemia, Myeloid, Acute

Share to Mutation

Share to Nucleophosmin

Share to Prognosis

Source

Identifiers

PMID: 33812399
DOI: 10.19746/j.cnki.issn.1009-2137.2021.02.008

Genes

IDH2
NPM1
ASXL1
FLT3
CD22
CD34
DNMT3A
IDH1
NRAS
TET2
U2AF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[Mutational Spectrum and Prognosis Analysis of AML Patients Based on High-Throughput Sequencing].PMID 33812399Read ↗

[Using next generation sequencing technology to analyze gene mutations in patients with acute myeloid leukemia and the impact on prognosis].Semantic proximity Read ↗

[Comparision of Mutational Spectrum between Elderly and Young Adults with Acute Myeloid Leukemia Based on Next Generation Sequencing].Semantic proximity Read ↗

[Analysis of Genomic Landscape in Patients with Acute Myeloid Leukemia].Semantic proximity Read ↗

Mutational spectrum and risk stratification of intermediate-risk acute myeloid leukemia patients based on next-generation sequencing.Semantic proximity Read ↗

[Prognostic significance of different IDH mutations and accompanying gene mutations in patients with acute myeloid leukemia].Semantic proximity Read ↗

Genomic Mutation Profiles of Patients with Acute Myeloid Leukemia in Korea: a Single-Center Experience.Semantic proximity Read ↗

[Application of Next Generation Sequencing for AML/MDS Diagnosis and Treatment].Semantic proximity Read ↗

Molecular Profiling of Acute Myeloid Leukemia in Pakistan: Comprehensive Variant Landscape Revealed by Targeted NGS.Semantic proximity Read ↗

Characteristics, clinical outcome, and prognostic significance of IDH mutations in AML.Semantic proximity Read ↗

[Genetic Mutation Profile and Risk Stratification of Cytogenetically Normal Acute Myeloid Leukemia with CEBPA-bZIP Mutations Based on Multi-Gene Sequencing].Semantic proximity Read ↗

Mutations in AML: prognostic and therapeutic implications.Semantic proximity Read ↗

Molecular Mutations and Their Cooccurrences in Cytogenetically Normal Acute Myeloid LeukemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.