Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic Mutations in Patients with Acute Myeloid Leukemia and Their Impact on Prognosis.

Clinical laboratory - 1 Sept 2026

Wu Chan, Chen Simin, Wei Haoyu, Yang Xiaofeng, Chen Yingying, Li Yan, Zhang Zhihua, Yang Xinhong

Abstract excerpt

BACKGROUND: This study aimed to analyze the mutant gene profile of patients with acute myeloid leukemia (AML) and discuss the value of genetic mutations in disease prognosis stratification. METHODS: Clinical data of patients newly diagnosed with AML (excluding acute promyelocytic leukemia, APL), who were admitted to the Department of Hematology of our hospital from October 2018 through October 2023, were...

Read the complete abstract on PubMed

Topics

Humans
Leukemia, Myeloid, Acute
Nucleophosmin
Male
Mutation
Prognosis
Adolescent

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Female

Child

Aged, 80 and over

Adult

Middle Aged

Aged

Young Adult

Biomarkers, Tumor

Source

Identifiers

PMID: 42733996
DOI: 10.7754/Clin.Lab.2025.250963

Genes

FLT3
NPM1
ASXL1
DNMT3A
NRAS
RUNX1
IDH2
IDH1
PTPN11
TET2
TP53
KIT
SRSF2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic Mutations in Patients with Acute Myeloid Leukemia and Their Impact on Prognosis.PMID 42733996Read ↗

Genomic Mutation Profiles of Patients with Acute Myeloid Leukemia in Korea: a Single-Center Experience.Semantic proximity Read ↗

Genomic mutation patterns and prognostic value in de novo and secondary acute myeloid leukemia: A multicenter study from China.Semantic proximity Read ↗

[Using next generation sequencing technology to analyze gene mutations in patients with acute myeloid leukemia and the impact on prognosis].Semantic proximity Read ↗

Mutations in AML: prognostic and therapeutic implications.Semantic proximity Read ↗

Gene mutations in acute myeloid leukemia.Semantic proximity Read ↗

Updates in molecular genetics of acute myeloid leukemia.Semantic proximity Read ↗

Molecular and clinical significance of FLT3, NPM1, DNMT3A and TP53 mutations in acute myeloid leukemia patients.Semantic proximity Read ↗

[Gene Mutation and Clinical Characteristics of Patients with Acute Leukemia].Semantic proximity Read ↗

Molecular Profiling of Acute Myeloid Leukemia in Pakistan: Comprehensive Variant Landscape Revealed by Targeted NGS.Semantic proximity Read ↗

[Analysis of Genomic Landscape in Patients with Acute Myeloid Leukemia].Semantic proximity Read ↗

The Mutational Landscape of Acute Myeloid Leukemia and Its Impact.Semantic proximity Read ↗

[Clinical characteristics of RUNX1-mutated acute myeloid leukemia patients].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.