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Article

Genes identified through genome-wide association studies of osteonecrosis in childhood acute lymphoblastic leukemia patients.

Pharmacogenomics - 1 Nov 2019

Gagné Vincent, Aubry-Morin Anne, Plesa Maria, Abaji Rachid, Petrykey Kateryna, St-Onge Pascal, Beaulieu Patrick, Laverdière Caroline, Alos Nathalie, Leclerc Jean-Marie, Sallan Stephen E, Neuberg Donna, Kutok Jeffery L, Silverman Lewis B, Sinnett Daniel, Krajinovic Maja

Abstract excerpt

Aim: To evaluate top-ranking genes identified through genome-wide association studies for an association with corticosteroid-related osteonecrosis in children with acute lymphoblastic leukemia (ALL) who received Dana-Farber Cancer Institute treatment protocols. Patients & methods: Lead SNPs from these studies, as well as other variants in the same genes, pooled from whole exome sequencing data, were analyzed for...

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Share to Adrenal Cortex Hormones
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Proteins

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Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

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Identifiers

PMID: 31686588
DOI: 10.2217/pgs-2019-0087
PMCID: PMC7026765

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