Article
Genetic factors contributing to late adverse musculoskeletal effects in childhood acute lymphoblastic leukemia survivors.
The pharmacogenomics journal - 1 Feb 2022
Shalmiev A, Nadeau G, Aaron M, Ouimet-Grennan E, Drouin S, Bertout L, Beaulieu P, St-Onge P, Veilleux L-N, Rauch F, Rezgui A, Petrykey K, Laverdière C, Sinnett D, Alos N, Krajinovic M
Abstract excerpt
BACKGROUND: A substantial number of survivors of childhood acute lymphoblastic leukemia (ALL) suffer from treatment-related late adverse effects. While multiple studies have identified the effects of chemotherapeutics and radiation therapy on musculoskeletal outcomes, few have investigated their associations with genetic factors. METHODS: Here we analyzed musculoskeletal complications in relation to common and...
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