Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A GRIN3A polymorphism may be associated with glucocorticoid-induced symptomatic osteonecrosis in children with acute lymphoblastic leukemia.

Personalized medicine - 1 Sept 2021

Zgheib Nathalie K, El-Khoury Habib, Maamari Dimitri, Basbous Maya, Saab Raya, Muwakkit Samar A

Abstract excerpt

Aim: To evaluate the association between candidate genetic polymorphisms and glucocorticoid-induced osteonecrosis in Arab children treated for acute lymphoblastic leukemia. Methods: A total of 189 children treated for acute lymphoblastic leukemia were genotyped for four SNPs with allele discrimination assays. The incidence and timing of radiologically confirmed symptomatic grade 4 osteonecrosis were classified...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucocorticoids

Share to Osteonecrosis

Share to Polymorphism, Single Nucleotide

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to Receptors, N-Methyl-D-Aspartate

Source

Identifiers

PMID: 34406079
DOI: 10.2217/pme-2020-0167

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A GRIN3A polymorphism may be associated with glucocorticoid-induced symptomatic osteonecrosis in children with acute lymphoblastic leukemia.PMID 34406079Read ↗

Genetics of glucocorticoid-associated osteonecrosis in children with acute lymphoblastic leukemia.Semantic proximity Read ↗

Pharmacokinetic, pharmacodynamic, and pharmacogenetic determinants of osteonecrosis in children with acute lymphoblastic leukemia.Semantic proximity Read ↗

Genetic Biomarkers to Identify the Risk of Osteonecrosis in Children with Acute Lymphoblastic Leukemia.Semantic proximity Read ↗

Genetic risk factors for the development of osteonecrosis in children under age 10 treated for acute lymphoblastic leukemia.Semantic proximity Read ↗

Comparing osteonecrosis clinical phenotype, timing, and risk factors in children and young adults treated for acute lymphoblastic leukemia.Semantic proximity Read ↗

ALL and osteonecrosis.Semantic proximity Read ↗

Pharmacogenetic Risk Factors for Osteonecrosis of the Hip Among Children With LeukemiaSemantic proximity Read ↗

Genetic Determinants of Treatment-Related Bone Toxicity in Pediatric Acute Lymphoblastic Leukemia.Semantic proximity Read ↗

Association Between NR3C1 Gene Polymorphisms and Toxicity Induced by Glucocorticoids Therapy in Saudi Children with Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Genetics of pleiotropic effects of dexamethasone.Semantic proximity Read ↗

Dual biomarkers long non-coding RNA GAS5 and its target, NR3C1, contribute to acute myeloid leukemia.Semantic proximity Read ↗

Genes identified through genome-wide association studies of osteonecrosis in childhood acute lymphoblastic leukemia patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.