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Article

Predictors of SIV recrudescence following antiretroviral treatment interruption

25 Oct 2019

Abstract excerpt

There is currently a need for proxy measures of the HIV rebound competent reservoir (RCR) that can predict viral rebound after combined antiretroviral treatment (cART) interruption. In this study, macaques infected with a barcoded SIVmac239 virus received cART beginning between 4- and 27 days post-infection, leading to the establishment of different levels of viral dissemination and persistence. Later treatment...

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PMID: 31650954
DOI: 10.7554/elife.49022

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