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Article

Compartmentalized HIV rebound in the central nervous system after interruption of antiretroviral therapy

1 Jul 2016

Abstract excerpt

To design effective eradication strategies, it may be necessary to target HIV reservoirs in anatomic compartments other than blood. This study examined HIV RNA rebound following interruption of antiretroviral therapy (ART) in blood and cerebrospinal fluid (CSF) to determine whether the central nervous system (CNS) might serve as an independent source of resurgent viral replication. Paired blood and CSF samples...

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PMID: 27774305
DOI: 10.1093/ve/vew020

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