Article
Importance and detection of virus reservoirs and compartments of HIV infection.
Current opinion in microbiology - 1 Aug 2003
Nickle David C, Shriner Daniel, Mittler John E, Frenkel Lisa M, Mullins James I
Abstract excerpt
Current therapies for treating HIV-1 infection are capable of suppressing virus load in blood to undetectable levels, and result in marked clinical improvement. Despite this suppression, HIV-1 infection persists and virus load quickly rebounds when therapy is interrupted. The origin of the rebounding virus is unknown, but is thought to result from continuing viral replication in anatomic or cellular compartments,...
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