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Article

Alzheimer's Disease Risk Variant rs2373115 Regulates GAB2 and NARS2 Expression in Human Brain Tissues.

Journal of molecular neuroscience : MN - 1 Sept 2018

Liu Guiyou, Wang Tao, Tian Rui, Hu Yang, Han Zhifa, Wang Pingping, Zhou Wenyang, Ren Peng, Zong Jian, Jin Shuilin, Jiang Qinghua

Abstract excerpt

Genetic association studies have identified significant association between the GAB2 rs2373115 variant and Alzheimer's disease (AD). However, it is unknown whether rs2373115 affects the regulation of nearby genes. Here, we evaluate the potential effect of rs2373115 on gene expression using multiple eQTL (expression quantitative trait loci) datasets from human brain tissues from the Mayo Clinic brain expression...

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Source

Identifiers

PMID: 30088171
DOI: 10.1007/s12031-018-1144-9

Genes

GAB2
NARS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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