Article
GAB2 as an Alzheimer disease susceptibility gene: follow-up of genomewide association results.
Archives of neurology - 1 Feb 2009
Schjeide Brit-Maren M, Hooli Basavaraj, Parkinson Michele, Hogan Meghan F, DiVito Jason, Mullin Kristina, Blacker Deborah, Tanzi Rudolph E, Bertram Lars
Abstract excerpt
BACKGROUND: Genomewide association (GWA) studies have recently implicated 4 novel Alzheimer disease (AD) susceptibility loci (GAB2, GOLM1, and 2 uncharacterized loci to date on chromosomes 9p and 15q). To our knowledge, these findings have not been independently replicated. OBJECTIVE: To assess these GWA findings in 4 large data sets of families affected by AD. DESIGN: Follow-up of genetic association findings in...
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