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Article

Alzheimer's Disease rs11767557 Variant Regulates EPHA1 Gene Expression Specifically in Human Whole Blood.

Journal of Alzheimer's disease : JAD - 1 Jan 2018

Liu Guiyou, Zhang Yan, Wang Longcai, Xu Jianyong, Chen Xiaoyun, Bao Yunjuan, Hu Yang, Jin Shuilin, Tian Rui, Bai Weiyang, Zhou Wenyang, Wang Tao, Han Zhifa, Zong Jian, Jiang Qinghua

Abstract excerpt

Large-scale genome-wide association studies have reported EPHA1 rs11767557 variant to be associated with Alzheimer's disease (AD) risk in the European population. However, it is still unclear how this variant functionally contributes to the underlying disease pathogenesis. The rs11767557 variant is located approximately 3 kb upstream of EPHA1 gene. We think that rs11767557 may modify the expression of nearby...

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Source

Identifiers

PMID: 29332039
DOI: 10.3233/JAD-170468

Genes

EPHA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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