Association analysis between polymorphism rs2373115 of gene GRB-associated binding protein 2 and Mongolian Alzheimer patients.

doi:10.1016/j.neulet.2010.02.047

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Article

Association analysis between polymorphism rs2373115 of gene GRB-associated binding protein 2 and Mongolian Alzheimer patients.

Neuroscience letters - 9 Aug 2010

Zhou Sirui, Huriletemuer, Wang Jing, Wang Binbin, Zhao Shigang, Wang De Sheng, Zhang Chunyu, Ma Xu

Abstract excerpt

GRB-associated binding protein 2 (GAB2) may function as a risk factor of Alzheimer disease (AD) by affecting hyperphosphorylation of tau, causing neurofibrillary tangles. There had been genomewide analysis discovering polymorphism rs2373115 correlated with AD and in this study we performed an association analysis on this polymorphism in 107:100 Mongolian Alzheimer patients and controls in order to discover...

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PMID: 20188796
DOI: 10.1016/j.neulet.2010.02.047

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GAB2

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