Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

ATP Binding Cassette Subfamily A Member 2 (ABCA2) Expression and Methylation are Associated with Alzheimer's Disease.

Medical science monitor : international medical journal of experimental and clinical research - 10 Dec 2017

Hu Wanhua, Lin Xiaodong, Zhang Huihe, Zhao Na

Abstract excerpt

BACKGROUND ABCA2 has been genetically linked to Alzheimer's disease (AD) risk, but its mRNA expression and epigenetics in AD have not been investigated. MATERIAL AND METHODS To explore the diagnosis value of ABCA2 mRNA expression in AD, 2 datasets GES15222 and GSE33000 containing expression profile of brain cortex tissues and 2 datasets GSE63063 (Cohort 1) and GSE63063 (Cohort 2) containing expression profile of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloid beta-Protein Precursor
Share to ATP-Binding Cassette Transporters

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cognitive Dysfunction

Share to CpG Islands

Share to Huntington Disease

Share to Methylation

Share to Tissue Array Analysis

Share to Up-Regulation

Source

Open in PubMed Open full text

Identifiers

PMID: 29224028
DOI: 10.12659/msm.905524
PMCID: PMC5733562

Genes

ABCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

ATP Binding Cassette Subfamily A Member 2 (ABCA2) Expression and Methylation are Associated with Alzheimer's Disease.PMID 29224028Read ↗

The role of ATP-binding cassette subfamily A in the etiology of Alzheimer’s diseaseSemantic proximity Read ↗

Gene Expression and Methylation Analysis of ABCA7 in Patients with Alzheimer's Disease.Semantic proximity Read ↗

Alzheimer's Disease and Effects of ABCA7 Polymorphisms: A Review.Semantic proximity Read ↗

ABC Transporters and the Alzheimer’s Disease EnigmaSemantic proximity Read ↗

ABCA7 expression is associated with Alzheimer's disease polymorphism and disease status.Semantic proximity Read ↗

The role of ABCA7 in Alzheimer’s disease: evidence from genomics, transcriptomics and methylomicsSemantic proximity Read ↗

Meta-Analysis of the Association between Variants in ABCA7 and Alzheimer's Disease.Semantic proximity Read ↗

Integrative Human Genetic and Cellular Analysis of the Pathophysiological Roles of AnxA2 in Alzheimer’s DiseaseSemantic proximity Read ↗

ABCA7-Associated Clinical Features and Molecular Mechanisms in Alzheimer’s DiseaseSemantic proximity Read ↗

ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease.Semantic proximity Read ↗

ATP binding cassette subfamily A member 7 rs3764650 polymorphism and the risk of Alzheimer's disease.Semantic proximity Read ↗

Differential Expression of mRNAs in the Brain Tissues of Patients with Alzheimer’s Disease Based on GEO Expression Profile and Its Clinical SignificanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.