Article
Implication of GAB2 gene polymorphism in Italian patients with Alzheimer's disease.
Journal of Alzheimer's disease : JAD - 1 Jan 2009
Nacmias Benedetta, Tedde Andrea, Bagnoli Silvia, Cellini Elena, Guarnieri Bianca Maria, Piacentini Silvia, Sorbi Sandro
Abstract excerpt
A common polymorphism (rs2373115) in the GRB-associated binding protein 2 (GAB2) gene has been recently associated with the risk of developing Alzheimer's disease (AD) in 644 apolipoprotein E (ApoE) epsilon4 carriers. In order to assess the involvement of the GAB2 polymorphism in the risk of developing AD, we analyzed the genotype and allele distributions of the GAB2 rs2373115 polymorphism in 579 Italian...
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