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Article

Age-Related Expression of Human AT1R Variants and Associated Renal Dysfunction in Transgenic Mice.

American journal of hypertension - 15 Oct 2018

Jain Sudhir, Rana Anita, Jain Kavita, Perla Sravan K, Puri Nitin, Kumar Ashok

Abstract excerpt

BACKGROUND: The contribution of single nucleotide polymorphisms in transcriptional regulation of the human angiotensin receptor type I (hAT1R) gene in age-related chronic pathologies such as hypertension and associated renal disorders is not well known. The hAT1R gene has single nucleotide polymorphisms in its promoter that forms 2 haplotypes (Hap), Hap-I and Hap-II. Hap-I of AT1R gene is associated with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30084918
DOI: 10.1093/ajh/hpy121
PMCID: PMC6454504

Genes

CRP
NOX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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