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Article

A transcription-centric model of SNP-Age interaction

2020-03-04

Abstract excerpt

Complex age-associated phenotypes are caused, in part, by an interaction between an individual’s genotype and age. The mechanisms governing such interactions are however not entirely understood. Here, we provide a novel transcriptional mechanism-based framework – SNiPage, to investigate such interactions, whereby a transcription factor (TF) whose expression changes with age (age-associated TF), binds to a polymorp...

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Literature Corpus work
a9a8b632-c73b-5878-887f-72c7a03cb6b8
DOI
10.1101/2020.03.02.973388
Open publication

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A transcription-centric model of SNP-Age interactionDOI 10.1101/2020.03.02.973388
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