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Article

Single-Nucleotide Polymorphisms (SNPs) Both Associated with Hypertension and Contributing to Accelerated-Senescence Traits in OXYS Rats.

International journal of molecular sciences - 17 May 2020

Devyatkin Vasiliy A, Redina Olga E, Muraleva Natalia A, Kolosova Nataliya G

Abstract excerpt

Aging is a major risk factor of numerous human diseases. Adverse genetic variants may contribute to multiple manifestations of aging and increase the number of comorbid conditions. There is evidence of links between hypertension and age-related diseases, although the genetic relationships are insufficiently studied. Here, we investigated the contribution of hypertension to the development of...

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PMID: 32429546
DOI: 10.3390/ijms21103542
PMCID: PMC7279015

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