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Article

Antisense-Derived HIV-1 Cryptic Epitopes Are Not Major Drivers of Viral Evolution during the Acute Phase of Infection.

Journal of virology - 1 Oct 2018

Peng Binghao J, Carlson Jonathan M, Liu Michael K P, Gao Feng, Goonetilleke Nilu, McMichael Andrew J, Borrow Persephone, Gilmour Jill, Heath Sonya L, Hunter Eric, Bansal Anju, Goepfert Paul A

Abstract excerpt

While prior studies have demonstrated that CD8 T cell responses to cryptic epitopes (CE) are readily detectable during HIV-1 infection, their ability to drive escape mutations following acute infection is unknown. We predicted 66 CE in a Zambian acute infection cohort based on escape mutations occurring within or near the putatively predicted HLA-I-restricted epitopes. The CE were evaluated for CD8 T cell...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30021907
DOI: 10.1128/JVI.00711-18
PMCID: PMC6146806

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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