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Article

Acute-phase CD8 T cell responses that select for escape variants are needed to control live attenuated simian immunodeficiency virus.

Journal of virology - 1 Aug 2013

Harris Max, Burns Charles M, Becker Ericka A, Braasch Andrew T, Gostick Emma, Johnson Randall C, Broman Karl W, Price David A, Friedrich Thomas C, O'Connor Shelby L

Abstract excerpt

The overall CD8 T cell response to human/simian immunodeficiency virus (HIV/SIV) targets a collection of discrete epitope specificities. Some of these epitope-specific CD8 T cells emerge in the weeks and months following infection and rapidly select for sequence variants, whereas other CD8 T cell responses develop during the chronic infection phase and rarely select for sequence variants. In this study, we tested...

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Share to CD8-Positive T-Lymphocytes
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immune Evasion

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Share to Simian Acquired Immunodeficiency Syndrome

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Source

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Identifiers

PMID: 23785211
DOI: 10.1128/JVI.00909-13
PMCID: PMC3754066

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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