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Article

Fitness-Balanced Escape Determines Resolution of Dynamic Founder Virus Escape Processes in HIV-1 Infection.

Journal of virology - 1 Oct 2015

Sunshine Justine E, Larsen Brendan B, Maust Brandon, Casey Ellie, Deng Wenje, Chen Lennie, Westfall Dylan H, Kim Moon, Zhao Hong, Ghorai Suvankar, Lanxon-Cookson Erinn, Rolland Morgane, Collier Ann C, Maenza Janine, Mullins James I, Frahm Nicole

Abstract excerpt

UNLABELLED: To understand the interplay between host cytotoxic T-lymphocyte (CTL) responses and the mechanisms by which HIV-1 evades them, we studied viral evolutionary patterns associated with host CTL responses in six linked transmission pairs. HIV-1 sequences corresponding to full-length p17 and p24 gag were generated by 454 pyrosequencing for all pairs near the time of transmission, and seroconverting...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to gag Gene Products, Human Immunodeficiency Virus

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Source

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Identifiers

PMID: 26223634
DOI: 10.1128/JVI.01876-15
PMCID: PMC4580195

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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