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Article

Viral evolution and escape during acute HIV-1 infection.

The Journal of infectious diseases - 15 Oct 2010

Boutwell Christian L, Rolland Morgane M, Herbeck Joshua T, Mullins James I, Allen Todd M

Abstract excerpt

The extensive genetic diversity of human immunodeficiency virus type 1 (HIV-1) presents a significant barrier to the development of an effective and durable HIV vaccine. This variability not only makes it difficult to identify the targets against which immune responses should be directed, but it also confers on the virus the capacity for rapid escape from effective immune responses. Here, we describe recent...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20846038
DOI: 10.1086/655653
PMCID: PMC2945609

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