Article
Determinants of myogenic specificity within MyoD are required for noncanonical E box binding.
Molecular and cellular biology - 1 Aug 2007
Heidt Analeah B, Rojas Anabel, Harris Ian S, Black Brian L
Abstract excerpt
The MyoD family of basic helix-loop-helix (bHLH) transcription factors has the remarkable ability to induce myogenesis in vitro and in vivo. This myogenic specificity has been mapped to two amino acids in the basic domain, an alanine and threonine, referred to as the myogenic code. These essential determinants of myogenic specificity are conserved in all MyoD family members from worms to humans, yet their...
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