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Article

A novel locus on mouse chromosome 7 that influences survival after infection with tick-borne encephalitis virus.

BMC neuroscience - 6 Jul 2018

Palus Martin, Sohrabi Yahya, Broman Karl W, Strnad Hynek, Šíma Matyáš, Růžek Daniel, Volkova Valeriya, Slapničková Martina, Vojtíšková Jarmila, Mrázková Lucie, Salát Jiří, Lipoldová Marie

Abstract excerpt

BACKGROUND: Tick-borne encephalitis (TBE) is the main tick-borne viral infection in Eurasia. Its manifestations range from inapparent infections and fevers with complete recovery to debilitating or fatal encephalitis. The basis of this heterogeneity is largely unknown, but part of this variation is likely due to host genetic. We have previously found that BALB/c mice exhibit intermediate susceptibility to the...

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PMID: 29976152
DOI: 10.1186/s12868-018-0438-8
PMCID: PMC6034256

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