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Article

A comprehensive genetic analysis of candidate genes regulating response to Trypanosoma congolense infection in mice.

PLoS neglected tropical diseases - 9 Nov 2010

Goodhead Ian, Archibald Alan, Amwayi Peris, Brass Andy, Gibson John, Hall Neil, Hughes Margaret A, Limo Moses, Iraqi Fuad, Kemp Stephen J, Noyes Harry A

Abstract excerpt

BACKGROUND: African trypanosomes are protozoan parasites that cause "sleeping sickness" in humans and a similar disease in livestock. Trypanosomes also infect laboratory mice and three major quantitative trait loci (QTL) that regulate survival time after infection with T. congolense have been identified in two independent crosses between susceptible A/J and BALB/c mice, and the resistant C57BL/6. These were...

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PMID: 21085469
DOI: 10.1371/journal.pntd.0000880
PMCID: PMC2976683

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PML

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