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Article

Genetic susceptibility to herpes simplex virus 1 encephalitis in mice and humans.

Current opinion in allergy and clinical immunology - 1 Dec 2007

Sancho-Shimizu Vanessa, Zhang Shen-Ying, Abel Laurent, Tardieu Marc, Rozenberg Flore, Jouanguy Emmanuelle, Casanova Jean-Laurent

Abstract excerpt

PURPOSE OF REVIEW: Herpes simplex encephalitis is a rare complication of herpes simplex virus 1 infection that strikes otherwise healthy individuals. Its pathogenesis has long remained elusive. We highlight the investigations dealing with the genetic basis of herpes simplex encephalitis in mice and humans. RECENT FINDINGS: Mouse models have revealed the impact of various host genes on protective immunity to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17989525
DOI: 10.1097/ACI.0b013e3282f151d2

Genes

TLR3
STAT1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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