Article
Mapping of a quantitative trait locus controlling susceptibility to Coxsackievirus B3-induced viral hepatitis.
Genes and immunity - 1 Jun 2015
Wiltshire S A, Marton J, Leiva-Torres G A, Vidal S M
Abstract excerpt
The pathogenesis of coxsackieviral infection is a multifactorial process involving host genetics, viral genetics and the environment in which they interact. We have used a mouse model of Coxsackievirus B3 infection to characterize the contribution of host genetics to infection survival and to viral hepatitis. Twenty-five AcB/BcA recombinant congenic mouse strains were screened. One, BcA86, was found to be...
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