Article
Multigenic control of resistance to Sendai virus infection in mice.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2009
Simon A Y, Moritoh K, Torigoe D, Asano A, Sasaki N, Agui T
Abstract excerpt
Experimental infection of mice with Sendai virus (SeV) is frequently used as a model of viral pathogenesis of human respiratory disease. To understand the differences in host response to SeV among mice strains, we carried out genetic mapping studies in DBA/2 (D2) (susceptible) and C57BL/6 (B6) (resistant) mice. F(1), F(2), and N(2) backcrossed mice were generated and examined for their disease resistance and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
