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Article

Genetic contribution of suppressor of cytokine signalling polymorphisms to the susceptibility to infection after traumatic injury.

Clinical and experimental immunology - 1 Oct 2018

Zhang A, Gu W, Lu H, Zeng L, Zhang L, Du D, Hao J, Wen D, Wang X, Jiang J

Abstract excerpt

Suppressor of cytokine signalling (SOCS) proteins are crucial negative regulators in many signalling pathways and are implicated in the pathogenesis of infectious diseases. The purpose of this study was to uncover possible associations of common polymorphisms within SOCS genes with infectious outcomes after traumatic injury. A total of 1087 trauma patients (Chongqing cohort 806 and Yunnan cohort 281) were...

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Identifiers

PMID: 29920655
DOI: 10.1111/cei.13160
PMCID: PMC6156814

Genes

CISH
TNF

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