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Article

A functional variant of lipopolysaccharide binding protein predisposes to sepsis and organ dysfunction in patients with major trauma.

Annals of surgery - 1 Jan 2012

Zeng Ling, Gu Wei, Zhang An-qiang, Zhang Mao, Zhang Lian-yang, Du Ding-yuan, Huang Su-na, Jiang Jian-Xin

Abstract excerpt

OBJECTIVE: To determine the hypothesis that genetic variations of the lipopolysaccharide-binding protein (LBP) gene influence risk for the development of sepsis and multiple organ dysfunction (MOD) in patients with major trauma. BACKGROUND: Lipopolysaccharide-binding protein plays a central role in innate immune response as the first line of defense and directing the microbial-induced activation of the...

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Source

Identifiers

PMID: 22167001
DOI: 10.1097/SLA.0b013e3182389515

Genes

LBP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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