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Article

Genetic variation in the tissue factor gene is associated with clinical outcome in severe sepsis patients.

Critical care (London, England) - 17 Nov 2014

Shi Dongwei, Song Zhenju, Yin Jun, Xue Mingming, Yao Chenling, Sun Zhan, Shao Mian, Deng Zhi, Zhang Yaping, Tao Zhengang, Sun Si, Zhang Jin, Xing Lingyu, Dong Zhimin, Wang Yuxin, Tong Chaoyang

Abstract excerpt

INTRODUCTION: Activation of inflammation and coagulation was closely related and mutually interdependent in sepsis. Tissue factor (TF) and its endogenous inhibitor, tissue factor pathway inhibitor (TFPI) was the main regulators of the initiation of coagulation process. Altered plasma levels of TF...

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Identifiers

PMID: 25407675
DOI: 10.1186/s13054-014-0631-9
PMCID: PMC4271362

Genes

TFPI

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25407675-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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