Article
Mutations that prevent methylation of cohesin render sensitivity to DNA damage in S. pombe.
Journal of cell science - 6 Jul 2018
Sanyal Swastika, Molnarova Lucia, Richterova Judita, Huraiova Barbora, Benko Zsigmond, Polakova Silvia, Cipakova Ingrid, Sevcovicova Andrea, Gaplovska-Kysela Katarina, Mechtler Karl, Cipak Lubos, Gregan Juraj
Abstract excerpt
The canonical role of cohesin is to mediate sister chromatid cohesion. In addition, cohesin plays important roles in processes such as DNA repair and regulation of gene expression. Mounting evidence suggests that various post-translational modifications, including phosphorylation, acetylation and sumoylation regulate cohesin functions. Our mass spectrometry analysis of cohesin purified from Schizosaccharomyces...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
