Article
A genetic screen to discover pathways affecting cohesin function in Schizosaccharomyces pombe identifies chromatin effectors.
G3 (Bethesda, Md.) - 1 Oct 2012
Chen Zhiming, McCrosky Scott, Guo Weichao, Li Hua, Gerton Jennifer L
Abstract excerpt
Cohesion, the force that holds sister chromatids together from the time of DNA replication until separation at the metaphase to anaphase transition, is mediated by the cohesin complex. This complex is also involved in DNA damage repair, chromosomes condensation, and gene regulation. To learn more about the cellular functions of cohesin, we conducted a genetic screen in Schizosaccharomyces pombe with two different...
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