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Article

Environmental enrichment reverses Aβ pathology during pregnancy in a mouse model of Alzheimer's disease.

Acta neuropathologica communications - 31 May 2018

Ziegler-Waldkirch Stephanie, Marksteiner Karin, Stoll Johannes, d'Errico Paolo, Friesen Marina, Eiler Denise, Neudel Lea, Sturn Verena, Opper Isabel, Datta Moumita, Prinz Marco, Meyer-Luehmann Melanie

Abstract excerpt

Several studies suggest that women have a higher risk to develop Alzheimer's disease (AD) than men. In particular, the number of pregnancies was shown to be a risk factor for AD and women with several pregnancies on average had an earlier onset of the disease, thus making childbearing a risk factor. However, the impact of being pregnant on Aβ plaque pathology and adult neurogenesis still remains elusive....

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PMID: 29855361
DOI: 10.1186/s40478-018-0549-6
PMCID: PMC5984325

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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