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Article

Perimenopause promotes neuroinflammation in select hippocampal regions in a mouse model of Alzheimer’s disease

2025-03-16

Abstract excerpt

<h4>ABSTRACT</h4> Alzheimer’s disease (AD) is the most common neurodegenerative disorder characterized by age-dependent amyloid beta (Aβ) aggregation and accumulation, neuroinflammation, and cognitive deficits. Significantly, there are prominent sex differences in the risk, onset, progression, and severity of AD, as well as response to therapies, with disease burden disproportionately affecting women. Although me...

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Literature Corpus work
0c986cbb-6788-51bf-8645-68aca742efdf
DOI
10.1101/2025.03.14.643317
Open publication

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Perimenopause promotes neuroinflammation in select hippocampal regions in a mouse model of Alzheimer’s diseaseDOI 10.1101/2025.03.14.643317
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