Article
Equilibrative nucleoside transporter 1 gene polymorphisms and clinical outcomes following acute coronary syndromes: findings from the PLATelet inhibition and patient Outcomes (PLATO) study.
Platelets - 1 Jan 2019
Parker William A E, Eriksson Niclas, Becker Richard C, Voora Deepak, Åkerblom Axel, Himmelmann Anders, James Stefan K, Wallentin Lars, Storey Robert F
Abstract excerpt
In the PLATelet inhibition and patient Outcomes (PLATO) study, the P2Y12 inhibitors ticagrelor and clopidogrel were compared in the treatment of acute coronary syndromes (ACS). Ticagrelor was shown to reduce occurrence of the primary end point - a composite of death from vascular causes, myocardial infarction, or stroke - compared to clopidogrel. Ticagrelor's pleiotropic effects on reuptake of adenosine via...
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