Article
Effects of four novel genetic polymorphisms on clopidogrel efficacy in Chinese acute coronary syndromes patients.
Gene - 5 Aug 2017
Xiao Fei-Yan, Liu Min, Chen Bi-Lian, Cao Shan, Fan Lan, Liu Zhao-Qian, Zhou Hong-Hao, Zhang Wei, Zhou Gan
Abstract excerpt
Dual antiplatelet therapy is the gold standard for the clinical treatment of coronary artery disease, especially for acute coronary syndromes patients. However, a substantial number of patients do not respond to clopidogrel despite a standardized dosage regimen, and this is directly associated with poor prognosis. Genetic polymorphisms may be one of the most important factors that contribute to this phenomenon....
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